diff --git a/runtime/filetype.vim b/runtime/filetype.vim
index 3ac1b62..02313fe 100644
--- a/runtime/filetype.vim
+++ b/runtime/filetype.vim
@@ -2840,6 +2840,7 @@
 " Xilinx Vivado/Vitis project files and block design files
 au BufNewFile,BufRead *.xpr,*.xpfm,*.spfm,*.bxml,*.mmi		setf xml
 au BufNewFile,BufRead *.bd,*.bda,*.xci				setf json
+au BufNewFile,BufRead *.mss					setf mss
 
 " XS Perl extension interface language
 au BufNewFile,BufRead *.xs			setf xs
diff --git a/runtime/ftplugin/mss.vim b/runtime/ftplugin/mss.vim
new file mode 100644
index 0000000..de2f879
--- /dev/null
+++ b/runtime/ftplugin/mss.vim
@@ -0,0 +1,16 @@
+" Vim filetype plugin file
+" Language:	Vivado mss file
+" Last Change:	2024 Oct 22
+" Document:	https://docs.amd.com/r/2020.2-English/ug1400-vitis-embedded/Microprocessor-Software-Specification-MSS
+" Maintainer:	Wu, Zhenyu <wuzhenyu@ustc.edu>
+
+if exists("b:did_ftplugin")
+  finish
+endif
+let b:did_ftplugin = 1
+
+setlocal comments=b:#,fb:-
+setlocal commentstring=#\ %s
+
+let b:match_words = '\<BEGIN\>:\<END\>'
+let b:undo_ftplugin = "setl com< cms< | unlet b:match_words"
diff --git a/runtime/syntax/mss.vim b/runtime/syntax/mss.vim
new file mode 100644
index 0000000..de95d1d
--- /dev/null
+++ b/runtime/syntax/mss.vim
@@ -0,0 +1,23 @@
+" Vim syntax file
+" Language:	Vivado mss file
+" Maintainer:	The Vim Project <https://github.com/vim/vim>
+" Last Change:	2024 Oct 22
+" Document:	https://docs.amd.com/r/2020.2-English/ug1400-vitis-embedded/Microprocessor-Software-Specification-MSS
+" Maintainer:	Wu, Zhenyu <wuzhenyu@ustc.edu>
+
+if exists("b:current_syntax")
+  finish
+endif
+
+syn case ignore
+syn match	mssComment	"#.*$" contains=@Spell
+syn keyword	mssKeyword	BEGIN END PARAMETER
+syn keyword	mssType		OS PROCESSOR DRIVER LIBRARY
+syn keyword	mssConstant	VERSION PROC_INSTANCE HW_INSTANCE OS_NAME OS_VER DRIVER_NAME DRIVER_VER LIBRARY_NAME LIBRARY_VER STDIN STDOUT XMDSTUB_PERIPHERAL ARCHIVER COMPILER COMPILER_FLAGS EXTRA_COMPILER_FLAGS
+
+hi def link mssComment		Comment
+hi def link mssKeyword		Keyword
+hi def link mssType		Type
+hi def link mssConstant		Constant
+
+let b:current_syntax = "mss"