diff --git a/src/screen.c b/src/screen.c
index b92cbf9..5dc8ffe 100644
--- a/src/screen.c
+++ b/src/screen.c
@@ -7828,7 +7828,7 @@
 	{
 	    if (attr > HL_ALL)				/* special HL attr. */
 	    {
-		if (t_colors > 1)
+		if (IS_CTERM)
 		    aep = syn_cterm_attr2entry(attr);
 		else
 		    aep = syn_term_attr2entry(attr);
@@ -7839,8 +7839,16 @@
 	    }
 	    if ((attr & HL_BOLD) && T_MD != NULL)	/* bold */
 		out_str(T_MD);
-	    else if (aep != NULL && t_colors > 1 && aep->ae_u.cterm.fg_color
-						      && cterm_normal_fg_bold)
+	    else if (aep != NULL && cterm_normal_fg_bold &&
+#ifdef FEAT_TERMTRUECOLOR
+			(p_guicolors ?
+			    (aep->ae_u.cterm.fg_rgb != INVALCOLOR):
+#endif
+			    (t_colors > 1 && aep->ae_u.cterm.fg_color)
+#ifdef FEAT_TERMTRUECOLOR
+			)
+#endif
+		    )
 		/* If the Normal FG color has BOLD attribute and the new HL
 		 * has a FG color defined, clear BOLD. */
 		out_str(T_ME);
@@ -7860,17 +7868,29 @@
 	     */
 	    if (aep != NULL)
 	    {
-		if (t_colors > 1)
+#ifdef FEAT_TERMTRUECOLOR
+		if (p_guicolors)
 		{
-		    if (aep->ae_u.cterm.fg_color)
-			term_fg_color(aep->ae_u.cterm.fg_color - 1);
-		    if (aep->ae_u.cterm.bg_color)
-			term_bg_color(aep->ae_u.cterm.bg_color - 1);
+		    if (aep->ae_u.cterm.fg_rgb != INVALCOLOR)
+			term_fg_rgb_color(aep->ae_u.cterm.fg_rgb);
+		    if (aep->ae_u.cterm.bg_rgb != INVALCOLOR)
+			term_bg_rgb_color(aep->ae_u.cterm.bg_rgb);
 		}
 		else
+#endif
 		{
-		    if (aep->ae_u.term.start != NULL)
-			out_str(aep->ae_u.term.start);
+		    if (t_colors > 1)
+		    {
+			if (aep->ae_u.cterm.fg_color)
+			    term_fg_color(aep->ae_u.cterm.fg_color - 1);
+			if (aep->ae_u.cterm.bg_color)
+			    term_bg_color(aep->ae_u.cterm.bg_color - 1);
+		    }
+		    else
+		    {
+			if (aep->ae_u.term.start != NULL)
+			    out_str(aep->ae_u.term.start);
+		    }
 		}
 	    }
 	}
@@ -7904,14 +7924,23 @@
 	    {
 		attrentry_T *aep;
 
-		if (t_colors > 1)
+		if (IS_CTERM)
 		{
 		    /*
 		     * Assume that t_me restores the original colors!
 		     */
 		    aep = syn_cterm_attr2entry(screen_attr);
-		    if (aep != NULL && (aep->ae_u.cterm.fg_color
-						 || aep->ae_u.cterm.bg_color))
+		    if (aep != NULL &&
+#ifdef FEAT_TERMTRUECOLOR
+			    (p_guicolors ?
+				(aep->ae_u.cterm.fg_rgb != INVALCOLOR ||
+				 aep->ae_u.cterm.bg_rgb != INVALCOLOR):
+#endif
+				(aep->ae_u.cterm.fg_color || aep->ae_u.cterm.bg_color)
+#ifdef FEAT_TERMTRUECOLOR
+			    )
+#endif
+			)
 			do_ME = TRUE;
 		}
 		else
@@ -7959,15 +7988,27 @@
 	    if (do_ME || (screen_attr & (HL_BOLD | HL_INVERSE)))
 		out_str(T_ME);
 
-	    if (t_colors > 1)
+#ifdef FEAT_TERMTRUECOLOR
+	    if (p_guicolors)
 	    {
-		/* set Normal cterm colors */
-		if (cterm_normal_fg_color != 0)
-		    term_fg_color(cterm_normal_fg_color - 1);
-		if (cterm_normal_bg_color != 0)
-		    term_bg_color(cterm_normal_bg_color - 1);
-		if (cterm_normal_fg_bold)
-		    out_str(T_MD);
+		if (cterm_normal_fg_gui_color != INVALCOLOR)
+		    term_fg_rgb_color(cterm_normal_fg_gui_color);
+		if (cterm_normal_bg_gui_color != INVALCOLOR)
+		    term_bg_rgb_color(cterm_normal_bg_gui_color);
+	    }
+	    else
+#endif
+	    {
+		if (t_colors > 1)
+		{
+		    /* set Normal cterm colors */
+		    if (cterm_normal_fg_color != 0)
+			term_fg_color(cterm_normal_fg_color - 1);
+		    if (cterm_normal_bg_color != 0)
+			term_bg_color(cterm_normal_bg_color - 1);
+		    if (cterm_normal_fg_bold)
+			out_str(T_MD);
+		}
 	    }
 	}
     }
@@ -7981,10 +8022,17 @@
     void
 reset_cterm_colors(void)
 {
-    if (t_colors > 1)
+    if (IS_CTERM)
     {
 	/* set Normal cterm colors */
+#ifdef FEAT_TERMTRUECOLOR
+	if (p_guicolors ?
+		(cterm_normal_fg_gui_color != INVALCOLOR
+		 || cterm_normal_bg_gui_color != INVALCOLOR):
+		(cterm_normal_fg_color > 0 || cterm_normal_bg_color > 0))
+#else
 	if (cterm_normal_fg_color > 0 || cterm_normal_bg_color > 0)
+#endif
 	{
 	    out_str(T_OP);
 	    screen_attr = -1;
@@ -8228,7 +8276,7 @@
 #ifdef FEAT_GUI
 	    !gui.in_use &&
 #endif
-			    t_colors <= 1);
+	    !IS_CTERM);
     for (row = start_row; row < end_row; ++row)
     {
 #ifdef FEAT_MBYTE
@@ -8911,6 +8959,9 @@
 #ifdef FEAT_GUI
 		|| gui.in_use
 #endif
+#ifdef FEAT_TERMTRUECOLOR
+		|| (p_guicolors && cterm_normal_bg_gui_color != INVALCOLOR)
+#endif
 		|| cterm_normal_bg_color == 0 || *T_UT != NUL));
 }
 
@@ -10242,6 +10293,9 @@
 #ifdef FEAT_GUI
 					    && !gui.in_use
 #endif
+#ifdef FEAT_TERMTRUECOLOR
+					    && !p_guicolors
+#endif
 					    );
 
     redraw_tabline = FALSE;