diff --git a/apex/apex.go b/apex/apex.go
index 4a9a9a3..ceaeaa0 100644
--- a/apex/apex.go
+++ b/apex/apex.go
@@ -29,6 +29,7 @@
 	"android/soong/android"
 	"android/soong/bpf"
 	"android/soong/cc"
+	"android/soong/dexpreopt"
 	prebuilt_etc "android/soong/etc"
 	"android/soong/filesystem"
 	"android/soong/java"
@@ -720,9 +721,15 @@
 	ctx.AddFarVariationDependencies(commonVariation, bpfTag, a.properties.Bpfs...)
 	ctx.AddFarVariationDependencies(commonVariation, fsTag, a.properties.Filesystems...)
 
-	// With EMMA_INSTRUMENT_FRAMEWORK=true the ART boot image includes jacoco library.
-	if a.artApex && ctx.Config().IsEnvTrue("EMMA_INSTRUMENT_FRAMEWORK") {
-		ctx.AddFarVariationDependencies(commonVariation, javaLibTag, "jacocoagent")
+	if a.artApex {
+		// With EMMA_INSTRUMENT_FRAMEWORK=true the ART boot image includes jacoco library.
+		if ctx.Config().IsEnvTrue("EMMA_INSTRUMENT_FRAMEWORK") {
+			ctx.AddFarVariationDependencies(commonVariation, javaLibTag, "jacocoagent")
+		}
+		// The ART boot image depends on dex2oat to compile it.
+		if !java.SkipDexpreoptBootJars(ctx) {
+			dexpreopt.RegisterToolDeps(ctx)
+		}
 	}
 
 	// Dependencies for signing
@@ -1520,6 +1527,9 @@
 		if dt, ok := depTag.(dependencyTag); ok && !dt.payload {
 			return false
 		}
+		if depTag == dexpreopt.Dex2oatDepTag {
+			return false
+		}
 
 		ai := ctx.OtherModuleProvider(child, android.ApexInfoProvider).(android.ApexInfo)
 		externalDep := !android.InList(ctx.ModuleName(), ai.InApexes)
@@ -1841,10 +1851,10 @@
 		return
 	}
 
-	// Specific to the ART apex: dexpreopt artifacts for libcore Java libraries. Build rules are
-	// generated by the dexpreopt singleton, and here we access build artifacts via the global
-	// boot image config.
 	if a.artApex {
+		// Specific to the ART apex: dexpreopt artifacts for libcore Java libraries. Build rules are
+		// generated by the dexpreopt singleton, and here we access build artifacts via the global
+		// boot image config.
 		for arch, files := range java.DexpreoptedArtApexJars(ctx) {
 			dirInApex := filepath.Join("javalib", arch.String())
 			for _, f := range files {
@@ -1853,6 +1863,11 @@
 				filesInfo = append(filesInfo, af)
 			}
 		}
+		// Call GetGlobalSoongConfig to initialize it, which may be necessary if dexpreopt is
+		// disabled for libraries/apps, but boot images are still needed.
+		if !java.SkipDexpreoptBootJars(ctx) {
+			dexpreopt.GetGlobalSoongConfig(ctx)
+		}
 	}
 
 	// Remove duplicates in filesInfo