diff --git a/cc/cc.go b/cc/cc.go
index 49fefe9..f65441f 100644
--- a/cc/cc.go
+++ b/cc/cc.go
@@ -211,6 +211,7 @@
 	selectedStl() string
 	baseModuleName() string
 	getVndkExtendsModuleName() string
+	isPgoCompile() bool
 }
 
 type ModuleContext interface {
@@ -408,6 +409,13 @@
 	return false
 }
 
+func (c *Module) isPgoCompile() bool {
+	if pgo := c.pgo; pgo != nil {
+		return pgo.Properties.PgoCompile
+	}
+	return false
+}
+
 func (c *Module) isVndkSp() bool {
 	if vndkdep := c.vndkdep; vndkdep != nil {
 		return vndkdep.isVndkSp()
@@ -507,6 +515,10 @@
 	return ctx.mod.isVndk()
 }
 
+func (ctx *moduleContextImpl) isPgoCompile() bool {
+	return ctx.mod.isPgoCompile()
+}
+
 func (ctx *moduleContextImpl) isVndkSp() bool {
 	return ctx.mod.isVndkSp()
 }
diff --git a/cc/lto.go b/cc/lto.go
index 4757fc7..2ced124 100644
--- a/cc/lto.go
+++ b/cc/lto.go
@@ -87,6 +87,13 @@
 			flags.LdFlags = append(flags.LdFlags, "-Wl,-plugin-opt,-emulated-tls")
 		}
 		flags.ArGoldPlugin = true
+
+		// If the module does not have a profile, be conservative and do not inline
+		// or unroll loops during LTO, in order to prevent significant size bloat.
+		if !ctx.isPgoCompile() {
+			flags.LdFlags = append(flags.LdFlags, "-Wl,-plugin-opt,-inline-threshold=0")
+			flags.LdFlags = append(flags.LdFlags, "-Wl,-plugin-opt,-unroll-threshold=0")
+		}
 	}
 	return flags
 }
diff --git a/cc/pgo.go b/cc/pgo.go
index 1e70339..779ef39 100644
--- a/cc/pgo.go
+++ b/cc/pgo.go
@@ -45,7 +45,7 @@
 	})
 }
 
-func recordMissingProfileFile(ctx ModuleContext, missing string) {
+func recordMissingProfileFile(ctx BaseModuleContext, missing string) {
 	getNamedMapForConfig(ctx.Config(), modulesMissingProfileFile).Store(missing, true)
 }
 
@@ -63,6 +63,7 @@
 
 	PgoPresent          bool `blueprint:"mutated"`
 	ShouldProfileModule bool `blueprint:"mutated"`
+	PgoCompile          bool `blueprint:"mutated"`
 }
 
 type pgo struct {
@@ -98,7 +99,7 @@
 	return flags
 }
 
-func (props *PgoProperties) getPgoProfileFile(ctx ModuleContext) android.OptionalPath {
+func (props *PgoProperties) getPgoProfileFile(ctx BaseModuleContext) android.OptionalPath {
 	// Test if the profile_file is present in any of the PGO profile projects
 	for _, profileProject := range getPgoProfileProjects(ctx.DeviceConfig()) {
 		path := android.ExistentPathForSource(ctx, "", profileProject, *props.Pgo.Profile_file)
@@ -232,6 +233,12 @@
 			}
 		}
 	}
+
+	if !ctx.Config().IsEnvTrue("ANDROID_PGO_NO_PROFILE_USE") {
+		if profileFile := pgo.Properties.getPgoProfileFile(ctx); profileFile.Valid() {
+			pgo.Properties.PgoCompile = true
+		}
+	}
 }
 
 func (pgo *pgo) deps(ctx BaseModuleContext, deps Deps) Deps {