diff --git a/cc/lto.go b/cc/lto.go
index 4757fc7..2ced124 100644
--- a/cc/lto.go
+++ b/cc/lto.go
@@ -87,6 +87,13 @@
 			flags.LdFlags = append(flags.LdFlags, "-Wl,-plugin-opt,-emulated-tls")
 		}
 		flags.ArGoldPlugin = true
+
+		// If the module does not have a profile, be conservative and do not inline
+		// or unroll loops during LTO, in order to prevent significant size bloat.
+		if !ctx.isPgoCompile() {
+			flags.LdFlags = append(flags.LdFlags, "-Wl,-plugin-opt,-inline-threshold=0")
+			flags.LdFlags = append(flags.LdFlags, "-Wl,-plugin-opt,-unroll-threshold=0")
+		}
 	}
 	return flags
 }