diff --git a/bp2build/cc_binary_conversion_test.go b/bp2build/cc_binary_conversion_test.go
index 1f69b5a..9e449eb 100644
--- a/bp2build/cc_binary_conversion_test.go
+++ b/bp2build/cc_binary_conversion_test.go
@@ -581,3 +581,32 @@
 		},
 	})
 }
+
+func TestCcBinaryWithInstructionSet(t *testing.T) {
+	runCcBinaryTests(t, ccBinaryBp2buildTestCase{
+		description: "instruction set",
+		blueprint: `
+{rule_name} {
+    name: "foo",
+    arch: {
+      arm: {
+        instruction_set: "arm",
+      }
+    }
+}
+`,
+		targets: []testBazelTarget{
+			{"cc_binary", "foo", AttrNameToString{
+				"features": `select({
+        "//build/bazel/platforms/arch:arm": [
+            "arm_isa_arm",
+            "-arm_isa_thumb",
+        ],
+        "//conditions:default": [],
+    })`,
+				"local_includes": `["."]`,
+			},
+			},
+		},
+	})
+}
diff --git a/bp2build/cc_library_conversion_test.go b/bp2build/cc_library_conversion_test.go
index 72feed5..2d1a7ce 100644
--- a/bp2build/cc_library_conversion_test.go
+++ b/bp2build/cc_library_conversion_test.go
@@ -2566,3 +2566,29 @@
 		},
 	})
 }
+
+func TestCcLibraryWithInstructionSet(t *testing.T) {
+	runCcLibraryTestCase(t, Bp2buildTestCase{
+		ModuleTypeUnderTest:        "cc_library",
+		ModuleTypeUnderTestFactory: cc.LibraryFactory,
+		Blueprint: `cc_library {
+    name: "foo",
+    arch: {
+      arm: {
+        instruction_set: "arm",
+      }
+    }
+}
+`,
+		ExpectedBazelTargets: makeCcLibraryTargets("foo", AttrNameToString{
+			"features": `select({
+        "//build/bazel/platforms/arch:arm": [
+            "arm_isa_arm",
+            "-arm_isa_thumb",
+        ],
+        "//conditions:default": [],
+    })`,
+			"local_includes": `["."]`,
+		}),
+	})
+}
diff --git a/cc/bp2build.go b/cc/bp2build.go
index 9880444..3fe0802 100644
--- a/cc/bp2build.go
+++ b/cc/bp2build.go
@@ -282,6 +282,8 @@
 	compilerAttributes
 	linkerAttributes
 
+	// A combination of compilerAttributes.features and linkerAttributes.features
+	features        bazel.StringListAttribute
 	protoDependency *bazel.LabelAttribute
 }
 
@@ -323,6 +325,8 @@
 
 	stubsSymbolFile *string
 	stubsVersions   bazel.StringListAttribute
+
+	features bazel.StringListAttribute
 }
 
 type filterOutFn func(string) bool
@@ -386,6 +390,13 @@
 	ca.absoluteIncludes.SetSelectValue(axis, config, props.Include_dirs)
 	ca.localIncludes.SetSelectValue(axis, config, localIncludeDirs)
 
+	instructionSet := proptools.StringDefault(props.Instruction_set, "")
+	if instructionSet == "arm" {
+		ca.features.SetSelectValue(axis, config, []string{"arm_isa_arm", "-arm_isa_thumb"})
+	} else if instructionSet != "" && instructionSet != "thumb" {
+		ctx.ModuleErrorf("Unknown value for instruction_set: %s", instructionSet)
+	}
+
 	// In Soong, cflags occur on the command line before -std=<val> flag, resulting in the value being
 	// overridden. In Bazel we always allow overriding, via flags; however, this can cause
 	// incompatibilities, so we remove "-std=" flags from Cflag properties while leaving it in other
@@ -686,9 +697,13 @@
 	(&compilerAttrs).srcs.Add(&convertedLSrcs.srcName)
 	(&compilerAttrs).cSrcs.Add(&convertedLSrcs.cSrcName)
 
+	features := compilerAttrs.features.Clone().Append(linkerAttrs.features)
+	features.DeduplicateAxesFromBase()
+
 	return baseAttributes{
 		compilerAttrs,
 		linkerAttrs,
+		*features,
 		protoDep.protoDep,
 	}
 }
diff --git a/cc/library.go b/cc/library.go
index 709dfef..521dcdf 100644
--- a/cc/library.go
+++ b/cc/library.go
@@ -359,7 +359,7 @@
 		C_std:                    compilerAttrs.cStd,
 		Use_version_lib:          linkerAttrs.useVersionLib,
 
-		Features: linkerAttrs.features,
+		Features: baseAttributes.features,
 	}
 
 	sharedTargetAttrs := &bazelCcLibrarySharedAttributes{
@@ -391,7 +391,7 @@
 			All:                          linkerAttrs.stripAll,
 			None:                         linkerAttrs.stripNone,
 		},
-		Features: linkerAttrs.features,
+		Features: baseAttributes.features,
 	}
 
 	if compilerAttrs.stubsSymbolFile != nil && len(compilerAttrs.stubsVersions.Value) > 0 {
@@ -2600,7 +2600,7 @@
 			Conlyflags: compilerAttrs.conlyFlags,
 			Asflags:    asFlags,
 
-			Features: linkerAttrs.features,
+			Features: baseAttributes.features,
 		}
 	} else {
 		commonAttrs.Dynamic_deps.Add(baseAttributes.protoDependency)
@@ -2637,7 +2637,7 @@
 				None:                         linkerAttrs.stripNone,
 			},
 
-			Features: linkerAttrs.features,
+			Features: baseAttributes.features,
 		}
 		if compilerAttrs.stubsSymbolFile != nil && len(compilerAttrs.stubsVersions.Value) > 0 {
 			hasStubs := true