diff --git a/dexpreopt/config.go b/dexpreopt/config.go
index 1844bce..7e73bf7 100644
--- a/dexpreopt/config.go
+++ b/dexpreopt/config.go
@@ -130,9 +130,11 @@
 	ProvidesUsesLibrary            string       // library name (usually the same as module name)
 	ClassLoaderContexts            ClassLoaderContextMap
 
-	Archs                         []android.ArchType
-	DexPreoptImagesDeps           []android.OutputPaths
-	DexPreoptImageLocationsOnHost []string // boot image location on host (file path without the arch subdirectory)
+	Archs               []android.ArchType
+	DexPreoptImagesDeps []android.OutputPaths
+
+	DexPreoptImageLocationsOnHost   []string // boot image location on host (file path without the arch subdirectory)
+	DexPreoptImageLocationsOnDevice []string // boot image location on device (file path without the arch subdirectory)
 
 	PreoptBootClassPathDexFiles     android.Paths // file paths of boot class path files
 	PreoptBootClassPathDexLocations []string      // virtual locations of boot class path files
diff --git a/dexpreopt/dexpreopt.go b/dexpreopt/dexpreopt.go
index 9d9234f..da015a3 100644
--- a/dexpreopt/dexpreopt.go
+++ b/dexpreopt/dexpreopt.go
@@ -499,11 +499,16 @@
 
 // PathToLocation converts .../system/framework/arm64/boot.art to .../system/framework/boot.art
 func PathToLocation(path android.Path, arch android.ArchType) string {
-	pathArch := filepath.Base(filepath.Dir(path.String()))
+	return PathStringToLocation(path.String(), arch)
+}
+
+// PathStringToLocation converts .../system/framework/arm64/boot.art to .../system/framework/boot.art
+func PathStringToLocation(path string, arch android.ArchType) string {
+	pathArch := filepath.Base(filepath.Dir(path))
 	if pathArch != arch.String() {
 		panic(fmt.Errorf("last directory in %q must be %q", path, arch.String()))
 	}
-	return filepath.Join(filepath.Dir(filepath.Dir(path.String())), filepath.Base(path.String()))
+	return filepath.Join(filepath.Dir(filepath.Dir(path)), filepath.Base(path))
 }
 
 func makefileMatch(pattern, s string) bool {
diff --git a/dexpreopt/dexpreopt_gen/dexpreopt_gen.go b/dexpreopt/dexpreopt_gen/dexpreopt_gen.go
index 32c4f84..7dbe74c 100644
--- a/dexpreopt/dexpreopt_gen/dexpreopt_gen.go
+++ b/dexpreopt/dexpreopt_gen/dexpreopt_gen.go
@@ -37,6 +37,12 @@
 	globalConfigPath      = flag.String("global", "", "path to global configuration file")
 	moduleConfigPath      = flag.String("module", "", "path to module configuration file")
 	outDir                = flag.String("out_dir", "", "path to output directory")
+	// If uses_target_files is true, dexpreopt_gen will be running on extracted target_files.zip files.
+	// In this case, the tool replace output file path with $(basePath)/$(on-device file path).
+	// The flag is useful when running dex2oat on system image and vendor image which are built separately.
+	usesTargetFiles = flag.Bool("uses_target_files", false, "whether or not dexpreopt is running on target_files")
+	// basePath indicates the path where target_files.zip is extracted.
+	basePath = flag.String("base_path", ".", "base path where images and tools are extracted")
 )
 
 type builderContext struct {
@@ -134,32 +140,28 @@
 			}
 		}
 	}()
-
+	if *usesTargetFiles {
+		moduleConfig.ManifestPath = android.OptionalPath{}
+		prefix := "dex2oat_result"
+		moduleConfig.BuildPath = android.PathForOutput(ctx, filepath.Join(prefix, moduleConfig.DexLocation))
+		for i, location := range moduleConfig.PreoptBootClassPathDexLocations {
+			moduleConfig.PreoptBootClassPathDexFiles[i] = android.PathForSource(ctx, *basePath+location)
+		}
+		for i := range moduleConfig.ClassLoaderContexts {
+			for _, v := range moduleConfig.ClassLoaderContexts[i] {
+				v.Host = android.PathForSource(ctx, *basePath+v.Device)
+			}
+		}
+		moduleConfig.EnforceUsesLibraries = false
+		for i, location := range moduleConfig.DexPreoptImageLocationsOnDevice {
+			moduleConfig.DexPreoptImageLocationsOnHost[i] = *basePath + location
+		}
+	}
 	writeScripts(ctx, globalSoongConfig, globalConfig, moduleConfig, *dexpreoptScriptPath)
 }
 
 func writeScripts(ctx android.BuilderContext, globalSoong *dexpreopt.GlobalSoongConfig,
 	global *dexpreopt.GlobalConfig, module *dexpreopt.ModuleConfig, dexpreoptScriptPath string) {
-	dexpreoptRule, err := dexpreopt.GenerateDexpreoptRule(ctx, globalSoong, global, module)
-	if err != nil {
-		panic(err)
-	}
-
-	installDir := module.BuildPath.InSameDir(ctx, "dexpreopt_install")
-
-	dexpreoptRule.Command().FlagWithArg("rm -rf ", installDir.String())
-	dexpreoptRule.Command().FlagWithArg("mkdir -p ", installDir.String())
-
-	for _, install := range dexpreoptRule.Installs() {
-		installPath := installDir.Join(ctx, strings.TrimPrefix(install.To, "/"))
-		dexpreoptRule.Command().Text("mkdir -p").Flag(filepath.Dir(installPath.String()))
-		dexpreoptRule.Command().Text("cp -f").Input(install.From).Output(installPath)
-	}
-	dexpreoptRule.Command().Tool(globalSoong.SoongZip).
-		FlagWithArg("-o ", "$2").
-		FlagWithArg("-C ", installDir.String()).
-		FlagWithArg("-D ", installDir.String())
-
 	write := func(rule *android.RuleBuilder, file string) {
 		script := &bytes.Buffer{}
 		script.WriteString(scriptHeader)
@@ -195,6 +197,30 @@
 			panic(err)
 		}
 	}
+	dexpreoptRule, err := dexpreopt.GenerateDexpreoptRule(ctx, globalSoong, global, module)
+	if err != nil {
+		panic(err)
+	}
+	// When usesTargetFiles is true, only odex/vdex files are necessary.
+	// So skip redunant processes(such as copying the result to the artifact path, and zipping, and so on.)
+	if *usesTargetFiles {
+		write(dexpreoptRule, dexpreoptScriptPath)
+		return
+	}
+	installDir := module.BuildPath.InSameDir(ctx, "dexpreopt_install")
+
+	dexpreoptRule.Command().FlagWithArg("rm -rf ", installDir.String())
+	dexpreoptRule.Command().FlagWithArg("mkdir -p ", installDir.String())
+
+	for _, install := range dexpreoptRule.Installs() {
+		installPath := installDir.Join(ctx, strings.TrimPrefix(install.To, "/"))
+		dexpreoptRule.Command().Text("mkdir -p").Flag(filepath.Dir(installPath.String()))
+		dexpreoptRule.Command().Text("cp -f").Input(install.From).Output(installPath)
+	}
+	dexpreoptRule.Command().Tool(globalSoong.SoongZip).
+		FlagWithArg("-o ", "$2").
+		FlagWithArg("-C ", installDir.String()).
+		FlagWithArg("-D ", installDir.String())
 
 	// The written scripts will assume the input is $1 and the output is $2
 	if module.DexPath.String() != "$1" {
diff --git a/java/dexpreopt.go b/java/dexpreopt.go
index 8d23ad6..2e46d74 100644
--- a/java/dexpreopt.go
+++ b/java/dexpreopt.go
@@ -184,7 +184,7 @@
 		imagesDeps = append(imagesDeps, variant.imagesDeps)
 	}
 	// The image locations for all Android variants are identical.
-	hostImageLocations := bootImage.getAnyAndroidVariant().imageLocations()
+	hostImageLocations, deviceImageLocations := bootImage.getAnyAndroidVariant().imageLocations()
 
 	var profileClassListing android.OptionalPath
 	var profileBootListing android.OptionalPath
@@ -224,9 +224,10 @@
 		ProvidesUsesLibrary:            providesUsesLib,
 		ClassLoaderContexts:            d.classLoaderContexts,
 
-		Archs:                         archs,
-		DexPreoptImagesDeps:           imagesDeps,
-		DexPreoptImageLocationsOnHost: hostImageLocations,
+		Archs:                           archs,
+		DexPreoptImagesDeps:             imagesDeps,
+		DexPreoptImageLocationsOnHost:   hostImageLocations,
+		DexPreoptImageLocationsOnDevice: deviceImageLocations,
 
 		PreoptBootClassPathDexFiles:     dexFiles.Paths(),
 		PreoptBootClassPathDexLocations: dexLocations,
diff --git a/java/dexpreopt_bootjars.go b/java/dexpreopt_bootjars.go
index ce68c48..45d4fe9 100644
--- a/java/dexpreopt_bootjars.go
+++ b/java/dexpreopt_bootjars.go
@@ -244,6 +244,9 @@
 	// Subdirectory where the image files are installed.
 	installDirOnHost string
 
+	// Subdirectory where the image files on device are installed.
+	installDirOnDevice string
+
 	// A list of (location, jar) pairs for the Java modules in this image.
 	modules android.ConfiguredJarList
 
@@ -273,8 +276,9 @@
 	dexLocationsDeps []string // for the dependency images and in this image
 
 	// Paths to image files.
-	imagePathOnHost android.OutputPath  // first image file
-	imagesDeps      android.OutputPaths // all files
+	imagePathOnHost   android.OutputPath  // first image file path on host
+	imagePathOnDevice string              // first image file path on device
+	imagesDeps        android.OutputPaths // all files
 
 	// Only for extensions, paths to the primary boot images.
 	primaryImages android.OutputPath
@@ -361,11 +365,12 @@
 // The location is passed as an argument to the ART tools like dex2oat instead of the real path.
 // ART tools will then reconstruct the architecture-specific real path.
 //
-func (image *bootImageVariant) imageLocations() (imageLocations []string) {
+func (image *bootImageVariant) imageLocations() (imageLocationsOnHost []string, imageLocationsOnDevice []string) {
 	if image.extends != nil {
-		imageLocations = image.extends.getVariant(image.target).imageLocations()
+		imageLocationsOnHost, imageLocationsOnDevice = image.extends.getVariant(image.target).imageLocations()
 	}
-	return append(imageLocations, dexpreopt.PathToLocation(image.imagePathOnHost, image.target.Arch.ArchType))
+	return append(imageLocationsOnHost, dexpreopt.PathToLocation(image.imagePathOnHost, image.target.Arch.ArchType)),
+		append(imageLocationsOnDevice, dexpreopt.PathStringToLocation(image.imagePathOnDevice, image.target.Arch.ArchType))
 }
 
 func dexpreoptBootJarsFactory() android.SingletonModule {
@@ -873,12 +878,13 @@
 		// Create a rule to call oatdump.
 		output := android.PathForOutput(ctx, "boot."+suffix+".oatdump.txt")
 		rule := android.NewRuleBuilder(pctx, ctx)
+		imageLocationsOnHost, _ := image.imageLocations()
 		rule.Command().
 			// TODO: for now, use the debug version for better error reporting
 			BuiltTool("oatdumpd").
 			FlagWithInputList("--runtime-arg -Xbootclasspath:", image.dexPathsDeps.Paths(), ":").
 			FlagWithList("--runtime-arg -Xbootclasspath-locations:", image.dexLocationsDeps, ":").
-			FlagWithArg("--image=", strings.Join(image.imageLocations(), ":")).Implicits(image.imagesDeps.Paths()).
+			FlagWithArg("--image=", strings.Join(imageLocationsOnHost, ":")).Implicits(image.imagesDeps.Paths()).
 			FlagWithOutput("--output=", output).
 			FlagWithArg("--instruction-set=", arch.String())
 		rule.Build("dump-oat-boot-"+suffix, "dump oat boot "+arch.String())
@@ -948,8 +954,8 @@
 				ctx.Strict("DEXPREOPT_IMAGE_BUILT_INSTALLED_"+sfx, variant.installs.String())
 				ctx.Strict("DEXPREOPT_IMAGE_UNSTRIPPED_BUILT_INSTALLED_"+sfx, variant.unstrippedInstalls.String())
 			}
-			imageLocations := current.getAnyAndroidVariant().imageLocations()
-			ctx.Strict("DEXPREOPT_IMAGE_LOCATIONS_"+current.name, strings.Join(imageLocations, ":"))
+			imageLocationsOnHost, _ := current.getAnyAndroidVariant().imageLocations()
+			ctx.Strict("DEXPREOPT_IMAGE_LOCATIONS_"+current.name, strings.Join(imageLocationsOnHost, ":"))
 			ctx.Strict("DEXPREOPT_IMAGE_ZIP_"+current.name, current.zip.String())
 		}
 		ctx.Strict("DEXPREOPT_IMAGE_NAMES", strings.Join(imageNames, " "))
diff --git a/java/dexpreopt_config.go b/java/dexpreopt_config.go
index 7fb0444..3724860 100644
--- a/java/dexpreopt_config.go
+++ b/java/dexpreopt_config.go
@@ -84,25 +84,28 @@
 		frameworkModules := global.BootJars.RemoveList(artModules)
 
 		artDirOnHost := "apex/art_boot_images/javalib"
+		artDirOnDevice := "apex/com.android.art/javalib"
 		frameworkSubdir := "system/framework"
 
 		// ART config for the primary boot image in the ART apex.
 		// It includes the Core Libraries.
 		artCfg := bootImageConfig{
-			name:             artBootImageName,
-			stem:             "boot",
-			installDirOnHost: artDirOnHost,
-			modules:          artModules,
+			name:               artBootImageName,
+			stem:               "boot",
+			installDirOnHost:   artDirOnHost,
+			installDirOnDevice: artDirOnDevice,
+			modules:            artModules,
 		}
 
 		// Framework config for the boot image extension.
 		// It includes framework libraries and depends on the ART config.
 		frameworkCfg := bootImageConfig{
-			extends:          &artCfg,
-			name:             frameworkBootImageName,
-			stem:             "boot",
-			installDirOnHost: frameworkSubdir,
-			modules:          frameworkModules,
+			extends:            &artCfg,
+			name:               frameworkBootImageName,
+			stem:               "boot",
+			installDirOnHost:   frameworkSubdir,
+			installDirOnDevice: frameworkSubdir,
+			modules:            frameworkModules,
 		}
 
 		configs := map[string]*bootImageConfig{
@@ -131,11 +134,12 @@
 				arch := target.Arch.ArchType
 				imageDir := c.dir.Join(ctx, target.Os.String(), c.installDirOnHost, arch.String())
 				variant := &bootImageVariant{
-					bootImageConfig: c,
-					target:          target,
-					imagePathOnHost: imageDir.Join(ctx, imageName),
-					imagesDeps:      c.moduleFiles(ctx, imageDir, ".art", ".oat", ".vdex"),
-					dexLocations:    c.modules.DevicePaths(ctx.Config(), target.Os),
+					bootImageConfig:   c,
+					target:            target,
+					imagePathOnHost:   imageDir.Join(ctx, imageName),
+					imagePathOnDevice: filepath.Join("/", c.installDirOnDevice, arch.String(), imageName),
+					imagesDeps:        c.moduleFiles(ctx, imageDir, ".art", ".oat", ".vdex"),
+					dexLocations:      c.modules.DevicePaths(ctx.Config(), target.Os),
 				}
 				variant.dexLocationsDeps = variant.dexLocations
 				c.variants = append(c.variants, variant)