diff --git a/cc/sanitize.go b/cc/sanitize.go
index 7fddc1b..6e732b6 100644
--- a/cc/sanitize.go
+++ b/cc/sanitize.go
@@ -665,6 +665,21 @@
 		s.Diag.Cfi = nil
 	}
 
+	// TODO(b/280478629): runtimes don't exist for musl arm64 yet.
+	if ctx.toolchain().Musl() && ctx.Arch().ArchType == android.Arm64 {
+		s.Address = nil
+		s.Hwaddress = nil
+		s.Thread = nil
+		s.Scudo = nil
+		s.Fuzzer = nil
+		s.Cfi = nil
+		s.Diag.Cfi = nil
+		s.Misc_undefined = nil
+		s.Undefined = nil
+		s.All_undefined = nil
+		s.Integer_overflow = nil
+	}
+
 	// Also disable CFI for VNDK variants of components
 	if ctx.isVndk() && ctx.useVndk() {
 		s.Cfi = nil