diff --git a/rust/sanitize.go b/rust/sanitize.go
index 536fcbd..a3c5cb5 100644
--- a/rust/sanitize.go
+++ b/rust/sanitize.go
@@ -174,7 +174,7 @@
 	}
 
 	// Enable Memtag for all components in the include paths (for Aarch64 only)
-	if ctx.Arch().ArchType == android.Arm64 {
+	if ctx.Arch().ArchType == android.Arm64 && ctx.Os().Bionic() {
 		if ctx.Config().MemtagHeapSyncEnabledForPath(ctx.ModuleDir()) {
 			if s.Memtag_heap == nil {
 				s.Memtag_heap = proptools.BoolPtr(true)
@@ -200,7 +200,7 @@
 	}
 
 	// HWASan requires AArch64 hardware feature (top-byte-ignore).
-	if ctx.Arch().ArchType != android.Arm64 {
+	if ctx.Arch().ArchType != android.Arm64 || !ctx.Os().Bionic() {
 		s.Hwaddress = nil
 	}
 
@@ -215,7 +215,7 @@
 	}
 
 	// Memtag_heap is only implemented on AArch64.
-	if ctx.Arch().ArchType != android.Arm64 {
+	if ctx.Arch().ArchType != android.Arm64 || !ctx.Os().Bionic() {
 		s.Memtag_heap = nil
 	}
 
@@ -234,7 +234,7 @@
 	}
 	if Bool(sanitize.Properties.Sanitize.Fuzzer) {
 		flags.RustFlags = append(flags.RustFlags, fuzzerFlags...)
-		if ctx.Arch().ArchType == android.Arm64 {
+		if ctx.Arch().ArchType == android.Arm64 && ctx.Os().Bionic() {
 			flags.RustFlags = append(flags.RustFlags, hwasanFlags...)
 		} else {
 			flags.RustFlags = append(flags.RustFlags, asanFlags...)
@@ -282,13 +282,13 @@
 		var deps []string
 
 		if mod.IsSanitizerEnabled(cc.Asan) ||
-			(mod.IsSanitizerEnabled(cc.Fuzzer) && mctx.Arch().ArchType != android.Arm64) {
+			(mod.IsSanitizerEnabled(cc.Fuzzer) && (mctx.Arch().ArchType != android.Arm64 || !mctx.Os().Bionic())) {
 			variations = append(variations,
 				blueprint.Variation{Mutator: "link", Variation: "shared"})
 			depTag = cc.SharedDepTag()
 			deps = []string{config.LibclangRuntimeLibrary(mod.toolchain(mctx), "asan")}
 		} else if mod.IsSanitizerEnabled(cc.Hwasan) ||
-			(mod.IsSanitizerEnabled(cc.Fuzzer) && mctx.Arch().ArchType == android.Arm64) {
+			(mod.IsSanitizerEnabled(cc.Fuzzer) && mctx.Arch().ArchType == android.Arm64 && mctx.Os().Bionic()) {
 			// TODO(b/204776996): HWASan for static Rust binaries isn't supported yet.
 			if binary, ok := mod.compiler.(binaryInterface); ok {
 				if binary.staticallyLinked() {