diff --git a/java/dex_test.go b/java/dex_test.go
index 97fc3d0..2ba3831 100644
--- a/java/dex_test.go
+++ b/java/dex_test.go
@@ -23,7 +23,7 @@
 )
 
 func TestR8(t *testing.T) {
-	result := PrepareForTestWithJavaDefaultModulesWithoutFakeDex2oatd.RunTestWithBp(t, `
+	result := PrepareForTestWithJavaDefaultModules.RunTestWithBp(t, `
 		android_app {
 			name: "app",
 			srcs: ["foo.java"],
@@ -191,7 +191,7 @@
 
 	for _, tc := range testcases {
 		t.Run(tc.name, func(t *testing.T) {
-			fixturePreparer := PrepareForTestWithJavaDefaultModulesWithoutFakeDex2oatd
+			fixturePreparer := PrepareForTestWithJavaDefaultModules
 			if tc.unbundled {
 				fixturePreparer = android.GroupFixturePreparers(
 					fixturePreparer,
@@ -258,7 +258,7 @@
 }
 
 func TestR8Flags(t *testing.T) {
-	result := PrepareForTestWithJavaDefaultModulesWithoutFakeDex2oatd.RunTestWithBp(t, `
+	result := PrepareForTestWithJavaDefaultModules.RunTestWithBp(t, `
 		android_app {
 			name: "app",
 			srcs: ["foo.java"],
@@ -287,7 +287,7 @@
 }
 
 func TestD8(t *testing.T) {
-	result := PrepareForTestWithJavaDefaultModulesWithoutFakeDex2oatd.RunTestWithBp(t, `
+	result := PrepareForTestWithJavaDefaultModules.RunTestWithBp(t, `
 		java_library {
 			name: "foo",
 			srcs: ["foo.java"],
@@ -328,7 +328,7 @@
 }
 
 func TestProguardFlagsInheritance(t *testing.T) {
-	result := PrepareForTestWithJavaDefaultModulesWithoutFakeDex2oatd.RunTestWithBp(t, `
+	result := PrepareForTestWithJavaDefaultModules.RunTestWithBp(t, `
 		android_app {
 			name: "app",
 			static_libs: [
diff --git a/java/dexpreopt.go b/java/dexpreopt.go
index 0ffedf6..a96b312 100644
--- a/java/dexpreopt.go
+++ b/java/dexpreopt.go
@@ -180,6 +180,8 @@
 	return android.RemoveOptionalPrebuiltPrefix(ctx.ModuleName())
 }
 
+// Returns whether dexpreopt is applicable to the module.
+// When it returns true, neither profile nor dexpreopt artifacts will be generated.
 func (d *dexpreopter) dexpreoptDisabled(ctx android.BaseModuleContext) bool {
 	if !ctx.Device() {
 		return true
@@ -205,14 +207,6 @@
 
 	global := dexpreopt.GetGlobalConfig(ctx)
 
-	if global.DisablePreopt {
-		return true
-	}
-
-	if inList(moduleName(ctx), global.DisablePreoptModules) {
-		return true
-	}
-
 	isApexSystemServerJar := global.AllApexSystemServerJars(ctx).ContainsJar(moduleName(ctx))
 	if isApexVariant(ctx) {
 		// Don't preopt APEX variant module unless the module is an APEX system server jar.
@@ -232,7 +226,7 @@
 }
 
 func dexpreoptToolDepsMutator(ctx android.BottomUpMutatorContext) {
-	if d, ok := ctx.Module().(DexpreopterInterface); !ok || d.dexpreoptDisabled(ctx) {
+	if d, ok := ctx.Module().(DexpreopterInterface); !ok || d.dexpreoptDisabled(ctx) || !dexpreopt.IsDex2oatNeeded(ctx) {
 		return
 	}
 	dexpreopt.RegisterToolDeps(ctx)
diff --git a/java/dexpreopt_test.go b/java/dexpreopt_test.go
index 3d2c5c3..f91ac5c 100644
--- a/java/dexpreopt_test.go
+++ b/java/dexpreopt_test.go
@@ -438,3 +438,28 @@
 
 	android.AssertIntEquals(t, "entries count", 0, len(entriesList))
 }
+
+func TestGenerateProfileEvenIfDexpreoptIsDisabled(t *testing.T) {
+	preparers := android.GroupFixturePreparers(
+		PrepareForTestWithJavaDefaultModules,
+		PrepareForTestWithFakeApexMutator,
+		dexpreopt.FixtureDisableDexpreopt(true),
+	)
+
+	result := preparers.RunTestWithBp(t, `
+		java_library {
+			name: "foo",
+			installable: true,
+			dex_preopt: {
+				profile: "art-profile",
+			},
+			srcs: ["a.java"],
+		}`)
+
+	ctx := result.TestContext
+	dexpreopt := ctx.ModuleForTests("foo", "android_common").MaybeRule("dexpreopt")
+
+	expected := []string{"out/soong/.intermediates/foo/android_common/dexpreopt/profile.prof"}
+
+	android.AssertArrayString(t, "outputs", expected, dexpreopt.AllOutputs())
+}