diff --git a/android/prebuilt.go b/android/prebuilt.go
index f3493bd..e611502 100644
--- a/android/prebuilt.go
+++ b/android/prebuilt.go
@@ -61,6 +61,16 @@
 	// a matching name.
 	Prefer *bool `android:"arch_variant"`
 
+	// When specified this names a Soong config variable that controls the prefer property.
+	//
+	// If the value of the named Soong config variable is true then prefer is set to false and vice
+	// versa. If the Soong config variable is not set then it defaults to false, so prefer defaults
+	// to true.
+	//
+	// If specified then the prefer property is ignored in favor of the value of the Soong config
+	// variable.
+	Use_source_config_var *ConfigVarProperties
+
 	SourceExists bool `blueprint:"mutated"`
 	UsePrebuilt  bool `blueprint:"mutated"`
 
@@ -68,6 +78,22 @@
 	PrebuiltRenamedToSource bool `blueprint:"mutated"`
 }
 
+// Properties that can be used to select a Soong config variable.
+type ConfigVarProperties struct {
+	// Allow instances of this struct to be used as a property value in a BpPropertySet.
+	BpPrintableBase
+
+	// The name of the configuration namespace.
+	//
+	// As passed to add_soong_config_namespace in Make.
+	Config_namespace *string
+
+	// The name of the configuration variable.
+	//
+	// As passed to add_soong_config_var_value in Make.
+	Var_name *string
+}
+
 type Prebuilt struct {
 	properties PrebuiltProperties
 
@@ -364,12 +390,18 @@
 		return false
 	}
 
-	// TODO: use p.Properties.Name and ctx.ModuleDir to override preference
-	if Bool(p.properties.Prefer) {
+	// If source is not available or is disabled then always use the prebuilt.
+	if source == nil || !source.Enabled() {
 		return true
 	}
 
-	return source == nil || !source.Enabled()
+	// If the use_source_config_var property is set then it overrides the prefer property setting.
+	if configVar := p.properties.Use_source_config_var; configVar != nil {
+		return !ctx.Config().VendorConfig(proptools.String(configVar.Config_namespace)).Bool(proptools.String(configVar.Var_name))
+	}
+
+	// TODO: use p.Properties.Name and ctx.ModuleDir to override preference
+	return Bool(p.properties.Prefer)
 }
 
 func (p *Prebuilt) SourceExists() bool {
diff --git a/android/prebuilt_test.go b/android/prebuilt_test.go
index 23524a5..dcd77ea 100644
--- a/android/prebuilt_test.go
+++ b/android/prebuilt_test.go
@@ -26,6 +26,7 @@
 	replaceBp bool // modules is added to default bp boilerplate if false.
 	modules   string
 	prebuilt  []OsType
+	preparer  FixturePreparer
 }{
 	{
 		name: "no prebuilt",
@@ -291,6 +292,86 @@
 			}`,
 		prebuilt: []OsType{Android, BuildOs},
 	},
+	{
+		name: "prebuilt use_source_config_var={acme, use_source} - no var specified",
+		modules: `
+			source {
+				name: "bar",
+			}
+
+			prebuilt {
+				name: "bar",
+				use_source_config_var: {config_namespace: "acme", var_name: "use_source"},
+				srcs: ["prebuilt_file"],
+			}`,
+		// When use_source_env is specified then it will use the prebuilt by default if the environment
+		// variable is not set.
+		prebuilt: []OsType{Android, BuildOs},
+	},
+	{
+		name: "prebuilt use_source_config_var={acme, use_source} - acme_use_source=false",
+		modules: `
+			source {
+				name: "bar",
+			}
+
+			prebuilt {
+				name: "bar",
+				use_source_config_var: {config_namespace: "acme", var_name: "use_source"},
+				srcs: ["prebuilt_file"],
+			}`,
+		preparer: FixtureModifyProductVariables(func(variables FixtureProductVariables) {
+			variables.VendorVars = map[string]map[string]string{
+				"acme": {
+					"use_source": "false",
+				},
+			}
+		}),
+		// Setting the environment variable named in use_source_env to false will cause the prebuilt to
+		// be used.
+		prebuilt: []OsType{Android, BuildOs},
+	},
+	{
+		name: "prebuilt use_source_config_var={acme, use_source} - acme_use_source=true",
+		modules: `
+			source {
+				name: "bar",
+			}
+
+			prebuilt {
+				name: "bar",
+				use_source_config_var: {config_namespace: "acme", var_name: "use_source"},
+				srcs: ["prebuilt_file"],
+			}`,
+		preparer: FixtureModifyProductVariables(func(variables FixtureProductVariables) {
+			variables.VendorVars = map[string]map[string]string{
+				"acme": {
+					"use_source": "true",
+				},
+			}
+		}),
+		// Setting the environment variable named in use_source_env to true will cause the source to be
+		// used.
+		prebuilt: nil,
+	},
+	{
+		name: "prebuilt use_source_config_var={acme, use_source} - acme_use_source=true, no source",
+		modules: `
+			prebuilt {
+				name: "bar",
+				use_source_config_var: {config_namespace: "acme", var_name: "use_source"},
+				srcs: ["prebuilt_file"],
+			}`,
+		preparer: FixtureModifyProductVariables(func(variables FixtureProductVariables) {
+			variables.VendorVars = map[string]map[string]string{
+				"acme": {
+					"use_source": "true",
+				},
+			}
+		}),
+		// Although the environment variable says to use source there is no source available.
+		prebuilt: []OsType{Android, BuildOs},
+	},
 }
 
 func TestPrebuilts(t *testing.T) {
@@ -329,6 +410,7 @@
 				}),
 				fs.AddToFixture(),
 				FixtureRegisterWithContext(registerTestPrebuiltModules),
+				OptionalFixturePreparer(test.preparer),
 			).RunTestWithBp(t, bp)
 
 			for _, variant := range result.ModuleVariantsForTests("foo") {